Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP7 All Species: 28.79
Human Site: S82 Identified Species: 45.24
UniProt: Q93009 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q93009 NP_003461.2 1102 128302 S82 V E R F S R L S E S V L S P P
Chimpanzee Pan troglodytes XP_510806 1102 128297 S82 V E R F S R L S E S V L S P P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536979 1086 126326 P72 L S E S V L S P P C F V R N L
Cat Felis silvestris
Mouse Mus musculus Q6A4J8 1103 128457 S83 V E R F S R L S E S V L S P P
Rat Rattus norvegicus Q4VSI4 1103 128413 S83 V E R F S R L S E S V L S P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506396 1145 132881 S125 V E R F S R L S E S V L S P P
Chicken Gallus gallus Q6U7I1 1101 128279 S82 V E R F N R L S E S V L S P P
Frog Xenopus laevis NP_001121282 534 61718
Zebra Danio Brachydanio rerio XP_691215 1103 128646 S83 V E R F S R L S E S V L S P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VYQ8 1129 130428 E95 G I D D E S K E D Q F R S E T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q7JKC3 1135 131579 G75 A I C R N Q Q G S R H S M N S
Sea Urchin Strong. purpuratus XP_780569 1189 136707 L174 E T S P T Q P L G D D V D T G
Poplar Tree Populus trichocarpa XP_002316470 1116 130731 S72 F N T K K L Y S D V F V V G G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84WU2 1115 130630 Y72 R L N T R K H Y S D V F V V G
Baker's Yeast Sacchar. cerevisiae P50101 1230 143545 N78 I L L F P Q G N H N K G V A V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 97.7 N.A. 99 99 N.A. 92.4 95.9 46 94 N.A. 48.5 N.A. 34.4 54.5
Protein Similarity: 100 99.9 N.A. 98 N.A. 99.7 99.8 N.A. 94.7 97.9 47.4 96.8 N.A. 67.5 N.A. 52.5 69.2
P-Site Identity: 100 100 N.A. 0 N.A. 100 100 N.A. 100 93.3 0 100 N.A. 6.6 N.A. 0 0
P-Site Similarity: 100 100 N.A. 13.3 N.A. 100 100 N.A. 100 100 0 100 N.A. 13.3 N.A. 13.3 20
Percent
Protein Identity: 36.9 N.A. N.A. 36.5 29.4 N.A.
Protein Similarity: 54.3 N.A. N.A. 54.7 47.8 N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: 20 N.A. N.A. 13.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % A
% Cys: 0 0 7 0 0 0 0 0 0 7 0 0 0 0 0 % C
% Asp: 0 0 7 7 0 0 0 0 14 14 7 0 7 0 0 % D
% Glu: 7 47 7 0 7 0 0 7 47 0 0 0 0 7 0 % E
% Phe: 7 0 0 54 0 0 0 0 0 0 20 7 0 0 0 % F
% Gly: 7 0 0 0 0 0 7 7 7 0 0 7 0 7 20 % G
% His: 0 0 0 0 0 0 7 0 7 0 7 0 0 0 0 % H
% Ile: 7 14 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 7 7 7 7 0 0 0 7 0 0 0 0 % K
% Leu: 7 14 7 0 0 14 47 7 0 0 0 47 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 7 7 0 14 0 0 7 0 7 0 0 0 14 0 % N
% Pro: 0 0 0 7 7 0 7 7 7 0 0 0 0 47 47 % P
% Gln: 0 0 0 0 0 20 7 0 0 7 0 0 0 0 0 % Q
% Arg: 7 0 47 7 7 47 0 0 0 7 0 7 7 0 0 % R
% Ser: 0 7 7 7 40 7 7 54 14 47 0 7 54 0 7 % S
% Thr: 0 7 7 7 7 0 0 0 0 0 0 0 0 7 7 % T
% Val: 47 0 0 0 7 0 0 0 0 7 54 20 20 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _